|  Help  |  About  |  Contact Us

Allele : Pik3ca<tm1Mawa> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1, Matthew Warman
Primary Identifier  MGI:6201353 Allele Type  Targeted
Attribute String  Conditional ready, Null/knockout Gene  Pik3ca
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct is designed to introduce a C420R point mutation (T2928C; TGT - CGT) into exon 8 of the gene with flanking loxP sites in introns 7 and 9. An FRT-flanked cassette containing the engrailed-2 strong splice acceptor and a reverse-orientation neomycin cassette under the control of the PGK promoter was also inserted immediately downstream of the intron 9 loxP site.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Pik3ca:C420R,
  • Pik3ca:C420R
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom