Primary Identifier | MGI:6201361 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Sox7 |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 1 sequence coding for the HMG box was targeted with oligonucleotides and sgRNAs using CRISPR/Cas9 technology. Three mouse lines with null alleles were established. This allele has a 28 bp deletion in the HMG box sequence that leads to a frameshift and a premature stop codon after 40 out-of-frame codons. |