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Allele : Sox7<em2Yokan> SRY (sex determining region Y)-box 7; endonuclease-mediated mutation 2, Yoshiakira Kanai

Primary Identifier  MGI:6201361 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Sox7
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 1 sequence coding for the HMG box was targeted with oligonucleotides and sgRNAs using CRISPR/Cas9 technology. Three mouse lines with null alleles were established. This allele has a 28 bp deletion in the HMG box sequence that leads to a frameshift and a premature stop codon after 40 out-of-frame codons.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Sox7-null,
  • Sox7-null
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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2 Publication categories

Trail: Allele