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Allele : Gt(ROSA)26Sor<tm1(CAG-MYCN,-luc)Jhsc> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Johannes H Schulte
Primary Identifier  MGI:6196127 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6 x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Recombinase-mediated cassette exchange (RMCE) replaced the selection cassette in Gt(ROSA)26Sortm1(CAG-flpe)Arte with a 5' deleted neomycin resistance cassette, the chicken actin gene (CAG) promoter, loxP flanked strong transcriptional termination site (LSL), the human MYCN gene, IRES, and the firefly luciferase gene. Cre-mediated recombination can be utilized to remove the transcription termination site 5' to the MYCN allele to get MYCN expression.
  • mutations:
  • Insertion
  • synonyms:
  • LSL-MYCN,
  • LSL-MYCN
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

13 Publication categories

Trail: Allele




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