| Primary Identifier | MGI:6209785 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(CAG-GBA*N409S)#Clk |
| Strain of Origin | C57BL/6 x CBA | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgenic construct contains the human GBA gene under the direction of CMV enhancer/chicken beta-actin promoter, rabbit beta-globin intron sequence and the rabbit globin polyA site (pCAGEN) promoter. GBA was modified by site-directed mutagenesis (c.1226A >G) to harbor an asparagine to serine mutation at residue 409 (referred to as N370S). |
