Primary Identifier | MGI:6220701 | Allele Type | Spontaneous |
Attribute String | Null/knockout | Gene | Lama2 |
Strain of Origin | Non-inbred stock | Is Recombinase | false |
Is Wild Type | false |
description | First observed in 1994 at the animal facility of the Pasteur Institute in Paris (France) in animals derived from a non-inbred agouti background (J:102806). |
molecularNote | This allele contains a 290 bp spontaneous insertion of the long terminal repeat of an intracisternal A-particle gene (IAP) and a 6.1 kb insertion of retrotransposon elements at nucleotide position 5113 (between exons 34 and 35). The translational reading frame is shifted from amino acid position 1706 and a stop codon appeared 12 codons later, producing a putative truncated protein devoid of domain I and II and the C-terminal G domain. |