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Allele : Lama2<dy-Pas> laminin, alpha 2; dystrophia muscularis Pasteur

Primary Identifier  MGI:6220701 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Lama2
Strain of Origin  Non-inbred stock Is Recombinase  false
Is Wild Type  false
description  First observed in 1994 at the animal facility of the Pasteur Institute in Paris (France) in animals derived from a non-inbred agouti background (J:102806).
molecularNote  This allele contains a 290 bp spontaneous insertion of the long terminal repeat of an intracisternal A-particle gene (IAP) and a 6.1 kb insertion of retrotransposon elements at nucleotide position 5113 (between exons 34 and 35). The translational reading frame is shifted from amino acid position 1706 and a stop codon appeared 12 codons later, producing a putative truncated protein devoid of domain I and II and the C-terminal G domain.
  • mutations:
  • Viral insertion,
  • Insertion
  • synonyms:
  • dy<Pas>,
  • dy<Pas>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele