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Allele : Mdm2<tm5.1Glo> transformed mouse 3T3 cell double minute 2; targeted mutation 5.1, Guillermina Lozano
Primary Identifier  MGI:6256961 Allele Type  Targeted
Gene  Mdm2 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  The critical C and G in the two Trp53 response elements in intron 1 were mutated. These mutations abolish the activity of the P2 promoter. An inverted floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the selection cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Mdm2<P2>,
  • Mdm2<P2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

5 Publication categories

Trail: Allele




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