| Primary Identifier | MGI:6278517 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Cox18 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAATCACTATGCTGCATGG and GTTGTTTGATGAGTTCATAA, which resulted in a 241 bp deletion beginning at Chromosome 5 position 90,222,124 bp and ending after 90,222,364 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000542644 (exon 2) and 140 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 108 and early truncation 17 amino acids later. |
