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Allele : Polr3b<em7(IMPC)Tcp> polymerase (RNA) III (DNA directed) polypeptide B; endonuclease-mediated mutation 7, The Centre for Phenogenomics

Primary Identifier  MGI:6257593 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Polr3b
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project TCPR0237 was generated at the Toronto Centre for Phenogenomics by injecting Cas9 D10A mRNA and a single guide RNA with the spacer sequence TCATGTCCCTCAGACGGCAC. This resulted in a 8 bp insertion TCCAGTGT at Chromosome 10 positive strand 84632456 bp (GRCm38) and is predicted to cause a frameshift mutation with early truncation. c.305_306insTCCAGTGT; p.R103Pfs*3.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele