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Allele : Dnah2<em1(IMPC)Tcp> dynein, axonemal, heavy chain 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Primary Identifier  MGI:6257800 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Dnah2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project TCPR1073 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GAGTCACACTAACCACCCCA and TGTTCTGGGCCGCAGGCACT targeting the 5' side and CAAATGCGTATAACCAGCGA and ATCACTACTCACGGTCACAA targeting the 3' side of a critical exon. This resulted in a 1295-bp deletion of Chr11 from 69483130 to 69484424 (GRCm38).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Dnah2<delta>,
  • Dnah2<delta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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