Primary Identifier | MGI:6258223 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(KRT5-Terf2)PNBlas |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The full-length mouse Terf2 cDNA was placed under control of the 5' regulatory region of the bovine keratin K5 promoter, which targets TERF2 to basal cells and stem cells of the epidermis. Three transgenic lines were generated and analyzed (PM, PN and PO). In the PN line (males and females), the levels of Terf2 mRNA expression in tail and back skin were ~12 times greater than those in wild-type controls. |