Primary Identifier | MGI:6258439 | Allele Type | Endonuclease-mediated |
Gene | Igdmr | Strain of Origin | (C57BL/6 x DBA/2)F2 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This differentially methylated region between Dlk1 and Gtl2 was targeted using CRISPR/Cas9 technology with a pair of sgRNAs flanking the 216 bp CpG-rich tandem repeat array in the center. Line C257 showed a 420 bp deletion that includes the entire repeat sequence and was selected for further study. |