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Allele : Igdmr<em2Takas> intergenic germline-derived differentially methylated region; endonuclease-mediated mutation 2, Shuji Takada

Primary Identifier  MGI:6258439 Allele Type  Endonuclease-mediated
Gene  Igdmr Strain of Origin  (C57BL/6 x DBA/2)F2
Is Recombinase  false Is Wild Type  false
molecularNote  This differentially methylated region between Dlk1 and Gtl2 was targeted using CRISPR/Cas9 technology with a pair of sgRNAs flanking the 216 bp CpG-rich tandem repeat array in the center. Line C257 showed a 420 bp deletion that includes the entire repeat sequence and was selected for further study.
  • mutations:
  • Intergenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele