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Allele : Ccsap<em1(IMPC)J> centriole, cilia and spindle associated protein; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6220921 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ccsap
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GAGTGGACTTTGGTTAACTG and GATAGCGATGGTGACTCCTG, which resulted in a 707 bp deletion beginning at Chromosome 8 position 123,845,017 bp and ending after 123,845,723 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000215358 (exon 2) and 441 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 105 and early truncation 2 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele