Primary Identifier | MGI:6269434 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Adra2a |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to C transition at base pair 54,046,639 (v38) on chromosome 19, or base pair 1,458 in the GenBank genomic region NC_000085 encoding Adra2a. The mutation corresponds to residue 1,458 in the mRNA sequence NM_007417 within exon 1 of 1 total exons. The mutation results in an isoleucine to threonine substitution at amino acid 142 (I142T) in the ADRA2A protein. |