| Primary Identifier | MGI:6268411 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Rbbp8nl |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCAGTGTCCCAAATGAAGAA and CTAGCTTAGCATCTGATTAG, which resulted in a 403 bp deletion beginning at Chromosome 2 position 180,283,188 bp and ending after 180,283,590 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000369913 (exon 3) and 360 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 20 and early truncation 5 amino acids later. |
