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Allele : Cacna1a<tm1Lory> calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; targeted mutation 1, Philippe Lory

Primary Identifier  MGI:6226076 Allele Type  Targeted
Attribute String  Dominant negative Gene  Cacna1a
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Point mutations, AGG codon at position 4489 to TGA, were inserted in exon 29 resulting in the R1497X missense mutation. The mutated codon leads to a premature stop at position 1497. The truncated channel lacks the fourth domain and C-terminus.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Cav2.1<R1497X>,
  • Cav2.1<R1497X>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele