Primary Identifier | MGI:6268750 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Nek8 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to C transition at base pair 78,173,059 (v38) on chromosome 11, or base pair 3,641 in the GenBank genomic region NC_000077. The mutation corresponds to residue 179 in the mRNA sequence NM_080849 within exon 2 of 15 total exons. The mutation results in a methionine to threonine substitution at position 40 (M40T) in the NEK8 protein. |