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Allele : Irf1<m2Btlr> interferon regulatory factor 1; mutation 2, Bruce Beutler

Primary Identifier  MGI:6269374 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Irf1
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced C to G transversion at base pair 53,771,322 (v38) on chromosome 11, or base pair 1,294 in the GenBank genomic region NC_000077. The mutation corresponds to residue 303 in the mRNA sequence NM_008390 within exon 2 of 10 total exons. The mutation results in a leucine to valine substitution at position 12 (L12V) in the IRF1 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • endeka2,
  • endeka2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele