Primary Identifier | MGI:6269378 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Irf1 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to A transversion at base pair 53,775,936 (v38) on chromosome 11, or base pair 5,923 in the GenBank genomic region NC_000077. The mutation corresponds to residue 1,008 in the mRNA sequence NM_008390 within exon 9 of 10 total exons. The mutation results in a tryptophan to arginine substitution at position 247 (W247R) in the IRF1 protein. |