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Allele : Irf1<M3Btlr> interferon regulatory factor 1; mutation 3, Bruce Beutler

Primary Identifier  MGI:6269378 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Irf1
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to A transversion at base pair 53,775,936 (v38) on chromosome 11, or base pair 5,923 in the GenBank genomic region NC_000077. The mutation corresponds to residue 1,008 in the mRNA sequence NM_008390 within exon 9 of 10 total exons. The mutation results in a tryptophan to arginine substitution at position 247 (W247R) in the IRF1 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Longs_peak,
  • Longs_peak
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele