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Allele : Gsdmd<em10Gpt> gasdermin D; endonuclease-mediated mutation 10, GemPharmatech Co., Ltd

Primary Identifier  MGI:6279768 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Gsdmd
Strain of Origin  C57BL/6NGpt Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing was used to generate a 127 bp deletion in exon 3 that results in a frame shift and subsequent introduction of a stop codon 32 condons downstream. qPCR confirmed complete deletion of the mRNA.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Gsdmd<em10Cd127>,
  • Gsdmd<em1Nju>,
  • Gsdmd<em10Cd127>,
  • Gsdmd<em1Nju>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele