| Primary Identifier | MGI:6258432 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Mrgbp |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCCCATTTACGGGCTGACCG and GGAAGTCAGGAGTGTCCCCA, which resulted in a 449 bp deletion beginning at Chromosome 2 position 180,583,115 bp and ending after 180,583,563 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001268049 (exon 3) and 327 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 49 and early truncation 3 amino acids later. |
