| Primary Identifier | MGI:6268722 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Irs1 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| molecularNote | ENU-induced T to A transversion at base pair 82,286,967 (v38) on chromosome 1, or base pair 4,473 in the GenBank genomic region NC_000067 encoding Irs1. The mutation corresponds to residue 4,473 in the mRNA sequence NM_010570 within exon 1 of 2 total exons. The mutation results in substitution of leucine 1,176 to a premature stop codon (L1176*) in the IRS1 protein. |
