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Allele : Insr<M2Btlr> insulin receptor; mutation 2, Bruce Beutler

Primary Identifier  MGI:6268734 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Insr
Inheritance Mode  Dominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to C transition at base pair 3,159,475 (v38) on chromosome 8, or base pair 120,175 in the GenBank genomic region NC_000074 encoding Insr. The mutation corresponds to residue 4,096 in the mRNA sequence NM_010568 within exon 19 of 21 total exons. The mutation results in a phenylalanine to leucine substitution at position 1,203 (F1203L) in the INSR protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Patently,
  • Patently
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele