|  Help  |  About  |  Contact Us

Allele : Abhd12b<em1(IMPC)J> abhydrolase domain containing 12B; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6274349 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Abhd12b
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGGATTTCCCTTACATGCCA and TATTGGGGAGAATTTATGTA, which resulted in a 416 bp deletion beginning at Chromosome 12 position 70,159,096 bp and ending after 70,159,511 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001266293 (exon 2) and 288 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 31 and early truncation 26 amino acids later.
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele