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Allele : Tg(Myh6-Camk2d_ic)MJhb transgene insertion M, Joan Heller Brown
Primary Identifier  MGI:6276040 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-Camk2d_ic)MJhb
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A hemagglutinin (HA)-tagged rat cDNA for the cytoplasmic variant of Camk2d is under the control of the 5.5-kb murine alpha-MHC promoter. Immunocytochemical staining confirmed that the expressed transgene is expressed only in the heart and is confined in the cytoplasm of cardiomyocytes. Three lines (TGL, TGM, and TGH) were generated. This TGM line carries 5 copies of the transgene and is the medium copy number line. Protein levels are increased 17-fold over wild-type levels but the amount of activated Camk2d is only increased 3-fold in hearts.
  • mutations:
  • Insertion
  • synonyms:
  • TGM,
  • TGM
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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