| Primary Identifier | MGI:6270168 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Camk2a-Polg*D181A)BTkato |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The mouse Polg cDNA in which an aspartate residue at position 181 was replaced with an alanine is under the control of the mouse calcium/calmodulin-activated protein kinase II alpha promoter. Three lines (A, B, and C) were generated. Line B is the high mRNA expressing line. RT-PCR confirmed expression of mRNA that is as abundant as the endogenous wild-type mRNA in most parts of the forebrain and mutant expression is nearly restricted in the brain. |
