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Allele : Lctl<tm1.1Gwis> lactase-like; targeted mutation 1.1 Graeme Wistow

Primary Identifier  MGI:6274975 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lctl
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1-7 were replaced with an frt-flanked neomycin selection cassette. The neomycin selection cassette was removed by FLP1-mediated recombination, leaving a single frt site in the final allele. Loss of mRNA and protein expression was confirmed by western blot and RNAseq experiments.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • KLPH KO,
  • KLPH KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele