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Allele : Plcg2<em1Bwef> phospholipase C, gamma 2; endonuclease-mediated mutation 1, Benedikt Wefers
Primary Identifier  MGI:6274477 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Plcg2
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9-mediated homologous recombination using a synthetic oligodeoxynucleotide created a nucleotide substitution (CCC to AGG) in exon 17 of Plcg2 that results in the amino acid substitution P522R. One additional silent nucleotide exchange within the protospacer region created a StuI restriction site for genotyping purposes.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Plcg2(P522R),
  • Plcg2<em1(P522R)Bwef>,
  • Plcg2 p.P522R,
  • Plcg2 p.P522R,
  • Plcg2<em1(P522R)Bwef>,
  • Plcg2(P522R)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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