Primary Identifier | MGI:6279994 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Tie1 |
Transmission | Germline | Strain of Origin | Not Specified |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A tamoxifen-inducible codon-improved Cre recombinase (iCre) flanked by two mutated estrogen receptor sites (MeriCreMer) and FRT-flanked Neo cassette was inserted into the first exon of the Tie1 locus in embryonic stem cells to express the fusion protein MeriCreMer under the control of the endogenous Tie1 promoter. |