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Allele : Scn2a<tm1.1Kzy> sodium channel, voltage-gated, type II, alpha; targeted mutation 1.1, Kazuhiro Yamakawa
Primary Identifier  MGI:6273225 Allele Type  Targeted
Attribute String  Humanized sequence, Null/knockout Gene  Scn2a
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site and FRT flanked neo cassette were inserted in intron 1 and an arginine to stop (p.Arg102*; c.304 CGG>TGA) mutation was inserted in exon 2 via homologous recombination. Flp-mediated recombination removed the neo cassette. Western blot analysis indicated lack of expression in whole brain lysates from homozygous mice.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Scn2a<RX>,
  • Scn2a<RX>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele




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