| Primary Identifier | MGI:6273209 | Allele Type | Targeted |
| Attribute String | Conditional ready, Humanized sequence | Gene | Lrrk2 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A proximal loxP site and FRT-flanked PGK-neomycin cassette were inserted in intron 41, a distal loxP site was inserted in intron 42, and G2019S mutation was inserted in exon 41 via homologous recombination. Flp mediated recombination removed the neo cassette. The expressed protein is resilient to kinase inhibition. |
