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Allele : Ergic1<em1(IMPC)J> endoplasmic reticulum-golgi intermediate compartment 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6294102 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ergic1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGAGCAGCCCGCTTCTACAG and GCTGGAGTGGAAATTACCAA, which resulted in a 365 bp deletion beginning at Chromosome 17 position 26,629,494 bp and ending after 26,629,858 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001241041 (exon 5) and 240 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 83 and early truncation 26 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele