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Allele : Rel<M2Btlr> reticuloendotheliosis oncogene; mutation 2, Bruce Beutler

Primary Identifier  MGI:6285776 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Rel
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3681
molecularNote  ENU-induced G to T transversion at base pair 23,757,026 (v38) on chromosome 11, or base pair 13,945 in the GenBank genomic region NC_000077. The mutation corresponds to residue 456 in the mRNA sequence NM_009044 within exon 3 of 10 total exons. The mutation results in substitution of glycine 59 for a premature stop codon (G59*) in the c-Rel protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Amun-ra,
  • Amun-ra
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele