| Primary Identifier | MGI:6294780 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Abca12 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGTGCTTAGATTGCCCCCAA and TTAGTCAACTGAAATTAATG, which resulted in a 254 bp deletion beginning at Chromosome 1 position 71,353,549 bp and ending after 71,353,802 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000441018 (exon 4) and 162 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 106 and early truncation 8 amino acids later. |
