Primary Identifier | MGI:6285919 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Lyn |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3777 |
molecularNote | ENU-induced C to T transition at base pair 3,748,787 (v38) on chromosome 4, or base pair 70,667 in the GenBank genomic region NC_000070 encoding Lyn. The mutation corresponds to residue 1,013 in the mRNA sequence NM_001111096 within exon 8 of 13 total exons. The mutation results in an alanine to valine substitution at position 255 (A255V) in the LYN protein. |