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Allele : Lyn<m4Btlr> LYN proto-oncogene, Src family tyrosine kinase; mutation 4, Bruce Beutler

Primary Identifier  MGI:6285919 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Lyn
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3777
molecularNote  ENU-induced C to T transition at base pair 3,748,787 (v38) on chromosome 4, or base pair 70,667 in the GenBank genomic region NC_000070 encoding Lyn. The mutation corresponds to residue 1,013 in the mRNA sequence NM_001111096 within exon 8 of 13 total exons. The mutation results in an alanine to valine substitution at position 255 (A255V) in the LYN protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • water,
  • water
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele