Primary Identifier | MGI:6286053 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Itgb2 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3760 |
molecularNote | ENU-induced T to C transition at base pair 77,549,968 (v38) on chromosome 10, or base pair 19,640 in the GenBank genomic region NC_000076. The mutation corresponds to residue 857 in the mRNA sequence NM_008404 within exon 7 of 16 total exons. The mutation results in a valine to alanine substitution at position 255 (V255A) in the integrin beta2 protein. |