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Allele : Itgb2<M4Btlr> integrin beta 2; mutation 4, Bruce Beutler

Primary Identifier  MGI:6286053 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Itgb2
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3760
molecularNote  ENU-induced T to C transition at base pair 77,549,968 (v38) on chromosome 10, or base pair 19,640 in the GenBank genomic region NC_000076. The mutation corresponds to residue 857 in the mRNA sequence NM_008404 within exon 7 of 16 total exons. The mutation results in a valine to alanine substitution at position 255 (V255A) in the integrin beta2 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Only_just,
  • Only_just
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele