| Primary Identifier | MGI:6273895 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(CST3*L68Q)#Efl |
| Strain of Origin | Swiss Webster | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | An 8.9 kb genomic fragment containing the human gene was micro-injected into single-cell embryos. This version of the gene contains a T>A mutation causing a p.Leu68Gln substitution in the encoded peptide. This mutation is found in patients suffering from hereditary cerebral hemorrhage with amyloidosis, Icelandic type (HCHWA-I). |
