| Primary Identifier | MGI:6277995 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Cwh43 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GATAAGAACTGTGTCTAGTA and CAATGGTCAGAACTTCGCCA, which resulted in a 259 bp deletion beginning at Chromosome 5 position 73,411,781 bp and ending after 73,412,039 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000186304 (exon 3) and 138 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 79 and early truncation 23 amino acids later. |
