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Allele : Tg(tetO-CHMP2B*)3Fbga transgene insertion 3, Fen-Biao Gao

Primary Identifier  MGI:6278302 Allele Type  Transgenic
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence Gene  Tg(tetO-CHMP2B*)3Fbga
Strain of Origin  Not Specified Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The human CHMP2B cDNA containing a missense mutation in the splice acceptor site of exon 6, a mutation identified in human familial FTD, is under the control of the tetracycline promoter. The mutation results in a truncation at the carboxy terminus such that the microtubule interacting and trafficking motif is lost.
  • mutations:
  • Insertion
  • synonyms:
  • CHMP2B<Intron5>,
  • CHMP2B<Intron5>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele