| Primary Identifier | MGI:6283556 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Tom1l1 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGCTATAAATAAGATTGCGG and TGTGATCTATCAATTTTGGA, which resulted in a 284 bp deletion beginning at Chromosome 11 position 90,683,198 bp and ending after 90,683,481 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000106324 (exon 3) and 205 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 48 and early truncation 15 amino acids later. |
