| Primary Identifier | MGI:6295435 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Nek1 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 genome editing is used to introduce the R549X mutation, and the silent A548A mutation. The mouse Nek1 R549X mutation is equivalent to the human R550X NEK1 mutation and is associated with amyotrophic lateral sclerosis. |
