Primary Identifier | MGI:6283435 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Fas |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3608 |
molecularNote | ENU-induced G to A transition at base pair 34,316,569 (v38) on chromosome 19, or base pair 24,659 in the GenBank genomic region NC_000085. The mutation corresponds to residue 379 in the mRNA sequence NM_007987 within exon 4 of 9 total exons. The mutation results in a glycine to aspartic acid substitution at position 108 (G108D) in the Fas protein. |