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Allele : Fas<m2Btlr> Fas cell surface death receptor; mutation 2, Bruce Beutler

Primary Identifier  MGI:6283435 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Fas
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3608
molecularNote  ENU-induced G to A transition at base pair 34,316,569 (v38) on chromosome 19, or base pair 24,659 in the GenBank genomic region NC_000085. The mutation corresponds to residue 379 in the mRNA sequence NM_007987 within exon 4 of 9 total exons. The mutation results in a glycine to aspartic acid substitution at position 108 (G108D) in the Fas protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • bing,
  • bing
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele