| Primary Identifier | MGI:6283534 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Serinc2 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGACAAAAGCCCCCCCCCAG and TTAGTGTTTAGAGCAACACG, which resulted in a 342 bp deletion beginning at Chromosome 4 position 130,264,223 bp and ending after 130,264,564 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000312129 (exon 3) and 151 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 12 and early truncation 4 amino acids later. |
