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Allele : Dock2<M9Btlr> dedicator of cyto-kinesis 2; mutation 9, Bruce Beutler

Primary Identifier  MGI:6284824 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Dock2
Inheritance Mode  Dominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3733
molecularNote  ENU-induced A to G transition at base pair 34,714,501 (v38) on chromosome 11, or base pair 69,409 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 872 in the mRNA sequence NM_178666 within exon 9 of 52 total exons. The mutation results in a lysine to glutamic acid substitution at position 264 (K264E) in the DOCK2 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Landing,
  • Landing
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele