Primary Identifier | MGI:6284824 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Dock2 |
Inheritance Mode | Dominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3733 |
molecularNote | ENU-induced A to G transition at base pair 34,714,501 (v38) on chromosome 11, or base pair 69,409 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 872 in the mRNA sequence NM_178666 within exon 9 of 52 total exons. The mutation results in a lysine to glutamic acid substitution at position 264 (K264E) in the DOCK2 protein. |