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Allele : Vav1<M4Btlr> vav 1 oncogene; mutation 4, Bruce Beutler

Primary Identifier  MGI:6285514 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Vav1
Inheritance Mode  Dominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3877
molecularNote  ENU-induced G to A transition at base pair 57,296,552 (v38) on chromosome 17, or base pair 17,021 in the GenBank genomic region NC_000083. The mutation corresponds to residue 420 in the mRNA sequence NM_011691 within exon 3 of 27 total exons. The mutation results in a valine to isoleucine substitution at amino acid 108 (V108I) in the VAV1 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Delayed,
  • Delayed
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele