Primary Identifier | MGI:6284778 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Nos3 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3796 |
molecularNote | ENU-induced G to A transition at base pair 24,377,855 (v38) on chromosome 5, or base pair 13,037 in the GenBank genomic region NC_000071. The mutation corresponds to residue 1,998 in the mRNA sequence NM_008713 within exon 16 of 26 total exons. The mutation results in a cysteine to tyrosine substitution at position 660 (C660Y) in the NOS3 protein. |