| Primary Identifier | MGI:6284807 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Jak3 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3764 |
| molecularNote | ENU-induced A to C transversion at base pair 71,683,978 (v38) on chromosome 8, or base pair 7,596 in the GenBank genomic region NC_000074 encoding Jak3. The mutation corresponds to residue 2,138 in the mRNA sequence NM_010589 within exon 15 of 25 total exons. The mutation results in an asparagine to threonine substitution at position 643 (N643T) in the JAK3 protein. |
