|  Help  |  About  |  Contact Us

Allele : Dock2<m8Btlr> dedicator of cyto-kinesis 2; mutation 8, Bruce Beutler

Primary Identifier  MGI:6284818 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Dock2
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3731
molecularNote  ENU-induced T to A transversion at base pair 34,689,766 (v38) on chromosome 11, or base pair 94,144 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 2,058 in the mRNA sequence NM_178666 within exon 20 of 52 total exons. The mutation results in an isoleucine to asparagine substitution at position 659 (I659N) in the DOCK2 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • pier,
  • pier
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele