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Allele : Lcn3<em3Btlr> lipocalin 3; endonuclease-mediated mutation 3, Bruce Beutler

Primary Identifier  MGI:6303844 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Lcn3
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The CRISPR/Cas9 system and sgRNA 5'-AGACGACATCCCAATAAACA-3' was used to generate the mice. The CRISPR/Cas9 system generated a 2-base pair deletion CA at c.391_392del (NM_010694.2). The mutation is predicted to cause a frame-shifted protein product beginning after amino acid 117 of the protein and termination after the inclusion of three aberrant amino acids.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele