Primary Identifier | MGI:6304291 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Lepr |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced C to A transversion at base pair 101,815,201 (v38) on chromosome 4, or base pair 98,068 in the GenBank genomic region NC_000070. The mutation corresponds to residue 3,973 in the mRNA sequence NM_146146 within exon 19 of 19 total exons. The mutation results in a glutamine to lysine substitution at position 1,141 (Q1141K) in the LEPR protein. |