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Allele : Nek2<em3(IMPC)Tcp> NIMA (never in mitosis gene a)-related expressed kinase 2; endonuclease-mediated mutation 3, The Centre for Phenogenomics

Primary Identifier  MGI:6316309 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Nek2
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPC309 was generated at The Centre for Phenogenomics by injecting Cas9D10A mRNA and guide RNAs with spacer sequences GGTCCCGGTGAAGCACAGTG and CAGCAAACACAATGTCAAGC, which resulted in an 8-bp deletion CTTCACCG in Chromosome 1 positive strand 191822588 bp (GRCm38) and is predicted to cause a frameshift mutation with early truncation. c.412_419delCTTCACCG; p.(L138Gfs*22)
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele